1: With potassium hydroxide in dimethyl sulfoxide T=20°C; 2: With water in dimethyl sulfoxide 0.5 h; 3: With hydrogenchloride in water; dimethyl sulfoxide
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2007/71358 A1, 2007 ;
Location in patent: Page/Page column 55 ;
WO 2007/071358 A1
1: With methanol; sodium hydroxide; water T=25°C; 24 h; 2: With hydrogenchloride; water in methanol T=0°C; pH=2;
参考文献
Zhu, Yuanming; Loso, Michael R.; Nugent, Benjamin M.; Huang, Jim X.; Rogers, Richard B.
Patent: US2008/108667 A1, 2008 ;
Location in patent: Page/Page column 10 ;
