T=180°C; 0.666667 h;

sodium hydroxide in ethanol; water 1 h; Heating;

in acetic acid

1: 98 percent / hydrogen / 5percent Rh/Al2O3 / ethyl acetate 2: 78.8 percent / 1 h / 110 °C 3: 47.3 percent / diphenyl ether / 1 h / Heating 4: 74.2 percent / potassium carbonate / dimethylformamide / 7 h / 70 °C 5: 51.3 percent / 2N NaOH / 2 h / Heating 6: acetic acid / 0.5 h / 140 °C View Scheme

1: 88.3 percent / acetic acid / 0.5 h / 130 °C 2: hydrogen / 5percent rhodium on alumina / aq. ethanol / 3040 Torr 3: 80.8 percent / aq. ethanol 4: 40.4 percent / diphenyl ether / 0.5 h / Heating 5: 60.9 percent / potassium carbonate powder / dimethylformamide / 4 h / 90 °C 6: 73.3 percent / 10percent aq sodium hydroxide / ethanol; H2O / 1 h / Heating View Scheme

1: hydrogen / 5percent rhodium on alumina / aq. ethanol / 3040 Torr 2: 80.8 percent / aq. ethanol 3: 40.4 percent / diphenyl ether / 0.5 h / Heating 4: 60.9 percent / potassium carbonate powder / dimethylformamide / 4 h / 90 °C 5: 73.3 percent / 10percent aq sodium hydroxide / ethanol; H2O / 1 h / Heating View Scheme

1: 51.3 percent / 2N NaOH / 2 h / Heating 2: acetic acid / 0.5 h / 140 °C View Scheme

1: 78.8 percent / 1 h / 110 °C 2: 47.3 percent / diphenyl ether / 1 h / Heating 3: 74.2 percent / potassium carbonate / dimethylformamide / 7 h / 70 °C 4: 51.3 percent / 2N NaOH / 2 h / Heating 5: acetic acid / 0.5 h / 140 °C View Scheme

1: 47.3 percent / diphenyl ether / 1 h / Heating 2: 74.2 percent / potassium carbonate / dimethylformamide / 7 h / 70 °C 3: 51.3 percent / 2N NaOH / 2 h / Heating 4: acetic acid / 0.5 h / 140 °C View Scheme

1: 74.2 percent / potassium carbonate / dimethylformamide / 7 h / 70 °C 2: 51.3 percent / 2N NaOH / 2 h / Heating 3: acetic acid / 0.5 h / 140 °C View Scheme