1: With oxalyl dichloride in toluene T=20°C; 3.5 h; 2: With tin(IV) chloride in dichloromethane Friedel-Crafts acylation; 2 h;

1: HF 2: NaOMe / benzene 3: (i) Et3N, benzene, (ii) KOH, MeOH 4: p-cymene / Pd-C / Heating 5: K2CO3 / acetone / Heating View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587189', constants.ctx, '0')">hydrogen</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '11378922', constants.ctx, '0')">palladium on activated charcoal</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a> <br /> <br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>1: (i) LiAlH₄, (ii) PBr₃ <br />2: ethanol<br />3: (i) NaOH, MeOH, (ii) /BRN= 102415/<br />4: LiAlH₄ <br />5: (i) PBr₃, (ii) /BRN= 774687/, NaH<br />6: (i) NaOH, MeOH, (ii) (thermolysis)<br /> <br /> &nbsp;