3,5-双(苄氧基)-N-(1-甲基-1H-吡唑-3-基)苯甲酰胺合成路线 (共 3 条)
反应条件
1: 3,5-bis(phenylmethoxy)benzoic acid With oxalyl dichloride in dichloromethane
T=20°C; 6 h;
2: 3-amino-1-methyl-pyrazole in dichloromethane
T=20°C; 16 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/7040 A1, 2007 ;
Location in patent: Page/Page column 70 ;
WO 2007/007040 A1
反应条件
in dichloromethane
T=20°C; 16 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/125972 A1, 2006 ;
Location in patent: Page/Page column 108; 109 ;
WO 2006/125972 A1
反应条件
ammonium formate; palladium 10 on activated carbon in ethanol
T=140°C; 0.0833333 h; Microwave;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/7040 A1, 2007 ;
Location in patent: Page/Page column 69-70 ;
WO 2007/007040 A1