5-(4-氯苯基)异噁唑-3-羰肼合成路线 （共 3 条）
反应条件
hydrazine hydrate in ethanol
4 h; Reflux;
参考文献
Dawood, Kamal M.; Abdel-Gawad, Hassan; Mohamed, Hanan A.; Badria, Farid A.
Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 912 - 919
反应条件
1: NH2OH*HCl, Na2CO3 / ethanol; H2O
2: N2H4*H2O / propan-2-ol; H2O
View Scheme
参考文献
Gardner,T.S. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1514 - 1518
反应条件
1: sodium ethanolate / ethanol
2: hydroxylamine hydrochloride; potassium carbonate / ethanol / Reflux
3: hydrazine hydrate / ethanol / 4 h / Reflux
View Scheme
参考文献
Dawood, Kamal M.; Abdel-Gawad, Hassan; Mohamed, Hanan A.; Badria, Farid A.
Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 912 - 919
