2-羟基-4,5,6-三甲基烟腈合成路线 （共 3 条）
反应条件
1: PCl5 / 180 °C
2: palladium/CaCO3; methanol / Hydrogenation
3: hydrochloric acid; sodium nitrite; water
4: thionyl chloride
5: palladium/calcium carbonate; methanol / Hydrogenation
View Scheme
参考文献
Tsuda et al.
Pharmaceutical Bulletin, 1953 , vol. 1, p. 122,125
反应条件
1: aqueous sulfuric acid
2: phosphorus (V)-chloride / 130 °C
3: hydriodic acid; zinc dust / 40 °C
View Scheme
参考文献
Guareschi
Chem. Zentralbl., 1900 , vol. 71, # I p. 1161
反应条件
1: aqueous sulfuric acid
2: phosphorus (V)-chloride / 130 °C
View Scheme
参考文献
Prelog et al.
Helvetica Chimica Acta, 1942 , vol. 25, p. 1654,1660
