3-[3-(4-甲基苯基)-1,2,4-恶二唑-5-基]苯胺合成路线 （共 4 条）
反应条件
1: 2-picoline / 0 - 20 °C
2: toluene / 3 h / |Reflux
3: zinc; ammonium chloride / methanol; tetrahydrofuran; water / 4 h / |Reflux
View Scheme
参考文献
He, Hai-Bing; Gao, Li-Xin; Zhou, Yue-Yang; Liu, Ting; Tang, Jie; Gong, Xue-Ping; Qiu, Wen-Wei; Li, Jing-Ya; Li, Jia; Yang, Fan
Heterocycles, 2012 , vol. 85, # 11 p. 2693 - 2712
反应条件
1: potassium carbonate; hydroxylamine hydrochloride / ethanol / 8 h / |Reflux
2: 2-picoline / 0 - 20 °C
3: toluene / 3 h / |Reflux
4: zinc; ammonium chloride / methanol; tetrahydrofuran; water / 4 h / |Reflux
View Scheme
参考文献
He, Hai-Bing; Gao, Li-Xin; Zhou, Yue-Yang; Liu, Ting; Tang, Jie; Gong, Xue-Ping; Qiu, Wen-Wei; Li, Jing-Ya; Li, Jia; Yang, Fan
Heterocycles, 2012 , vol. 85, # 11 p. 2693 - 2712
反应条件
ammonium chloride; zinc in tetrahydrofuran; methanol; water
4 h; Reflux;
参考文献
He, Hai-Bing; Gao, Li-Xin; Zhou, Yue-Yang; Liu, Ting; Tang, Jie; Gong, Xue-Ping; Qiu, Wen-Wei; Li, Jing-Ya; Li, Jia; Yang, Fan
Heterocycles, 2012 , vol. 85, # 11 p. 2693 - 2712
反应条件
1: 2-picoline / 0 - 20 °C
2: toluene / 3 h / |Reflux
3: zinc; ammonium chloride / methanol; tetrahydrofuran; water / 4 h / |Reflux
View Scheme
参考文献
He, Hai-Bing; Gao, Li-Xin; Zhou, Yue-Yang; Liu, Ting; Tang, Jie; Gong, Xue-Ping; Qiu, Wen-Wei; Li, Jing-Ya; Li, Jia; Yang, Fan
Heterocycles, 2012 , vol. 85, # 11 p. 2693 - 2712
