1-甲基-1H-四唑e-5-羧酸乙酯合成路线 （共 3 条）
反应条件
1: With sodium hydroxide; ethanol; water T=20°C; 2 h; 2: With hydrogenchloride; water in ethanol pH=4;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2008/150015 A1, 2008 ;
Location in patent: Page/Page column 175-176 ;
WO 2008/150015 A1
反应条件
potassium carbonate in acetonitrile
T=20°C; 15 h;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2008/150015 A1, 2008 ;
Location in patent: Page/Page column 176 ;
WO 2008/150015 A1
反应条件
sodium hydroxide in water; acetone
3 h; Heating; Yield given. Title compound not separated from byproducts;
参考文献
Spear, Robert J.
Australian Journal of Chemistry, 1984 , vol. 37, # 12 p. 2453 - 2468
