5-氯-1H-吡咯并[2,3-B]吡啶 7-氧化物合成路线 (共 3 条)
反应条件
3-chloro-benzenecarboperoxoic acid in ethyl acetate
T=0 - 20°C;
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2010/81645 A1, 2010 ;
Location in patent: Page/Page column 37 ;
反应条件
3-chloro-benzenecarboperoxoic acid in ethyl acetate
T=0 - 20°C; 35 h;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2006/127587 A1, 2006 ;
Location in patent: Page/Page column 86-87 ;
WO 2006/127587 A1
反应条件
[14C]-Tetramethylammonium bromide; trifluoromethanesulfonic anhydride in N,N-dimethyl-formamide
T=0 - 20°C; 2.5 h;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2006/127587 A1, 2006 ;
Location in patent: Page/Page column 87 ;
WO 2006/127587 A1