4-溴-5-氯-1H-吡咯并[2,3-b]吡啶合成路线 （共 2 条）
反应条件
[14C]-Tetramethylammonium bromide; trifluoromethanesulfonic anhydride in N,N-dimethyl-formamide
T=0 - 20°C; 2.5 h;
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2010/81645 A1, 2010 ;
Location in patent: Page/Page column 37 ;
反应条件
sodium hydride in N,N-dimethyl-formamide
T=0 - 20°C; 2 h;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2006/127587 A1, 2006 ;
Location in patent: Page/Page column 87-88 ;
WO 2006/127587 A1
