间(2-甲基-4-氯苯基)苯甲酸合成路线 （共 2 条）
反应条件
1: With sodium carbonate; palladium 10 on activated carbon in water; isopropyl alcohol
T=80°C; Suzuki Coupling;
2: With hydrogenchloride in water
pH=< 2;
参考文献
AMGEN INC
Patent: US2006/270724 A1, 2006 ;
Location in patent: Page/Page column 26 ;
US 20060270724 A1
反应条件
{C6H3[NHP(piperidinyl)2]2Pd(Cl)}; potassium carbonate in 1,4-dioxane; water; butan-1-ol
T=100°C; Suzuki-Miyaura reaction; 6 h;
参考文献
Bolliger, Jeanne L.; Frech, Christian M.
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 6 p. 1075 - 1080
