4-(BOC-甲基氨基)苯硼酸频那醇酯合成路线 （共 4 条）
反应条件
sodium hydride in N,N-dimethyl-formamide; mineral oil T=20°C; 18 h;
参考文献
Taisho Pharmaceutical Co., Ltd.; Toyama Chemical Co., Ltd.; TAKASHIMA, Hajime; TSURUTA, Risa; YABUUCHI, Tetsuya; OKA, Yusuke; URABE, Hiroki; SUGA, Yoichiro; TAKAHASHI, Masato; UNEUCHI, Fumito; KOTSUBO, Hironori; SHOJI, Muneo; KAWAGUCHI, Yasuko
Patent: EP2562155 A1, 2013 ;
Location in patent: Paragraph 0222-0223 ;
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in dimethyl sulfoxide T=80°C; Miyaura reaction; 3.5 h;
参考文献
Lin, Chen; Drueckhammer, Dale G.
New Journal of Chemistry, 2006 , vol. 30, # 12 p. 1725 - 1730
反应条件
1: 83 percent / Et3N; DMAP / CH2Cl2 / Heating 2: 63 percent / KOAc / PdCl2(dppf)*CH2Cl2 / dimethylsulfoxide / 3.5 h / 80 °C View Scheme
参考文献
New Journal of Chemistry, , vol. 30, # 12 p. 1725 - 1730
反应条件
1: 83 percent / Et3N; DMAP / CH2Cl2 / Heating 2: 63 percent / KOAc / PdCl2(dppf)*CH2Cl2 / dimethylsulfoxide / 3.5 h / 80 °C View Scheme
参考文献
New Journal of Chemistry, , vol. 30, # 12 p. 1725 - 1730
