in diethyl ether; benzene T=25°C; 1.5 h; Various pyridine ketones, the effect of ketone/CH3Li or PhLi ratio, LiBr and longer reaction time (150 h).; Product distribution;
参考文献
Epsztajn, Jan; Bieniek, Adam
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 213 - 220
1: in diethyl ether T=-78 - 0°C; 1 h; 2: With water in tetrahydrofuran; diethyl ether T=0°C; 0.166667 h; 3: With 2,3-dichloro-5,6-dicyanohydroquinone in tetrahydrofuran; diethyl ether T=0°C; 1 h;
参考文献
BANYU PHARMACEUTICAL CO., LTD.
Patent: EP1790650 A1, 2007 ;
Location in patent: Page/Page column 56 ;