反应条件
1: 1-t-butoxycarbonyl-4-aminopiperidine; α-bromoacetophenone With N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 17 h; 2: cyanic acid sodium salt With acetic acid in dichloromethane T=0 - 20°C; pH=4; 16 h;
参考文献
Gutierrez, Corey; Termin, Andreas; Hadida-Ruah, Sara; Joshi, Pramod; Bergeron, Daniele; Yoo, Sanghee; Binch, Hayley; Come, Jon; Cao, Jingrong; Nanthakumar, Suganthi
Patent: US2008/4261 A1, 2008 ;
Location in patent: Page/Page column 137 ;
US 20080004261 A1