N,N-二甲基-4-(1-哌嗪)苯胺合成路线 (共 5 条)
反应条件
1: ethanol / 24 h / Ambient temperature 2: methanol / 12 h / Ambient temperature View Scheme
参考文献
Bosc; Jarry; Carpy; Panconi; Descas
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 437 - 442
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Merck Sharpe and Dohme Ltd.
Patent: US5432177 A1, 1995 ;
反应条件
hydrogenchloride; sodium hydroxide; potassium carbonate; potassium hydroxide in ethanol; 2-butoxy-ethanol; water
参考文献
Rhone-Poulenc Sante
Patent: US4547504 A1, 1985 ;
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in methanol; water
P=2585.81 Torr; 71 h;
参考文献
Lauteslager, Xavier Y.; Van Stokkum, Ivo H. M.; Van John Ramesdonk; Bebelaar, Dick; Fraanje, Jan; Goubitz, Kees; Schenk, Henk; Brouwer, Albert M.; Verhoeven, Jan W.
European Journal of Organic Chemistry, 2001 , # 16 p. 3105 - 3118
反应条件
potassium hydroxide in ethanol
参考文献
Rhone-Poulenc Sante
Patent: US4547504 A1, 1985 ;