1.1: chloroform / 1.5 h / 60 °C 2.1: triethylamine / dichloromethane / 24 h / Reflux 3.1: acetic acid / 1,2-dichloro-ethane / 2 h / 60 °C 4.1: tetraphosphorus decasulfide; sodium carbonate / 1,2-dichloro-ethane / 2 h / 70 °C 5.1: hydrazine hydrate / tetrahydrofuran / 4 h / 0 - 15 °C 6.1: triethylamine / tetrahydrofuran / 1 h / 20 °C 7.1: acetic acid / tetrahydrofuran / 48 h / 20 °C 8.1: sodium hydroxide / tetrahydrofuran / 5 h / 20 °C 9.1: N-ethyl-N,N-diisopropylamine; HATU / tetrahydrofuran / 3 h / 20 °C 9.2: 48 h View Scheme