4-三氟甲基-联苯-2-羧酸甲酯合成路线 (共 4 条)
反应条件
sodium hydroxide in ethanol 5 h; Heating;
参考文献
Fukuyama, Takahide; Maetani, Shinji; Miyagawa, Kazusa; Ryu, Ilhyong
Organic Letters, 2014 , vol. 16, # 12 p. 3216 - 3219
反应条件
potassium phosphate; SBA-Si-PEG-Pd(PPh3)n in water
T=50°C; Suzuki coupling; 20 h;
参考文献
Yang, Qing; Ma, Shengming; Li, Jixue; Xiao, Fengshou; Xiong, Hai
Chemical Communications, 2006 , # 23 p. 2495 - 2497
反应条件
manganese; cobalt (II) bromide; triphenylphosphine; trifluoroacetic acid in pyridine; N,N-dimethyl-formamide
T=50°C;
参考文献
Amatore, Muriel; Gosmini, Corinne
Angewandte Chemie - International Edition, 2008 , vol. 47, # 11 p. 2089 - 2092
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate in ethylene glycol dimethyl ether
Suzuki coupling; 16 h; Heating;
参考文献
Ksander; DeJesus; Yuan; Fink; Moskal; Carlson; Kukkola; Bilci; Wallace; Neubert; Feldman; Mogelesky; Poirier; Jeune; Steele; Wasvery; Stephan; Cahill; Webb; Navarrete; Lee; Gibson; Alexander; Sharif; Hospattankar
Journal of Medicinal Chemistry, 2001 , vol. 44, # 26 p. 4677 - 4687