(R)-4-苄基-3-氰基甲基吗啉合成路线 (共 2 条)
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane; water
20 h; Heating / reflux;
参考文献
ASTRAZENECA AB
Patent: WO2006/137790 A1, 2006 ;
Location in patent: Page/Page column 33 ;
WO 2006/137790 A1
反应条件
1: With hydrogenchloride
T=20°C;
2: With sodium carbonate in water
参考文献
ASTRAZENECA AB
Patent: WO2006/137790 A1, 2006 ;
Location in patent: Page/Page column 33 ;
WO 2006/137790 A1