5-(3,4-二甲氧基苯基)-2H-四唑-2-基]乙酸合成路线 （共 3 条）
反应条件
sodium hydroxide
4 h; Heating;
参考文献
Maxwell, James R.; Wasdahl, Dan A.; Wolfson, Alan C.; Stenberg, Virgil I.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1565 - 1570
反应条件
1: 78 percent / NaN3, NH4Cl / dimethylformamide / 17 h / Heating
2: 1.) EtONa / 1.) EtOH, reflux, 2.) EtOH, reflux, 16 h
3: 73 percent / aq. NaOH / 4 h / Heating
View Scheme
参考文献
Maxwell, James R.; Wasdahl, Dan A.; Wolfson, Alan C.; Stenberg, Virgil I.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1565 - 1570
反应条件
1: 1.) EtONa / 1.) EtOH, reflux, 2.) EtOH, reflux, 16 h
2: 73 percent / aq. NaOH / 4 h / Heating
View Scheme
参考文献
Maxwell, James R.; Wasdahl, Dan A.; Wolfson, Alan C.; Stenberg, Virgil I.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1565 - 1570
