6-氯-4-[1,2,4]噻唑-1-基-吡啶并[3,2-d]嘧啶-2-基-胺合成路线 （共 3 条）
反应条件
N-ethyl-N,N-diisopropylamine; trichlorophosphate in acetonitrile
T=20°C; 240 h;
参考文献
Herdewijn, Piet Andre' Maurits Maria; De Jonghe, Steven Cesar Alfons; Watkins, William John; Chong, Lee Shun; Zhang, Jennifer
Patent: US2009/253696 A1, 2009 ;
Location in patent: Page/Page column 20 ;
反应条件
potassium tert-butylate in tetrahydrofuran; dichloromethane
T=20°C; 0.166667 h;
参考文献
GILEAD SCIENCES, INC.
Patent: WO2008/77649 A1, 2008 ;
Location in patent: Page/Page column 41-42; 59 ;
反应条件
potassium tert-butylate in tetrahydrofuran; dichloromethane
T=20°C; 0.5 h;
参考文献
GILEAD SCIENCES, INC.
Patent: WO2008/77649 A1, 2008 ;
Location in patent: Page/Page column 57 ;
