1: 73 percent / (+/-)-BINAP; Cs2CO3 / Pd2(dba)3 / toluene / 20 h / Heating 2: 72 percent / NaOMe / methanol / 4 h / Heating View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=20&deg;C;&nbsp;2&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 5.57 g / ethanol / 16 h / 78 &deg;C<br />2: 8.28 g / 2,6-lutidine / CH₂Cl₂ / 3 h / -78 - 20 &deg;C<br /> <br /> &nbsp;