5-(4-丁基苯基)-6-氯-n-环戊基-2-甲基嘧啶-4-胺合成路线 （共 2 条）
反应条件
potassium phosphate; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate in ethylene glycol dimethyl ether; water
T=85°C; Suzuki Coupling; 2 h;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2006/136442 A1, 2006 ;
Location in patent: Page/Page column 37-38 ;
WO 2006/136442 A1
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate in ethylene glycol dimethyl ether; water
T=85°C; Suzuki coupling;
参考文献
Guery, Sebastien; Floersheim, Philipp; Kaupmann, Klemens; Froestl, Wolfgang
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 22 p. 6206 - 6211
