lithium hydroxide in tetrahydrofuran; water T=20°C; 2 h;

1: 4-nitro-3-(tetrahydrofuran-3-yloxy)-benzoic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 0.25 h; 2: methylamine in tetrahydrofuran; dichloromethane T=20°C; 18 h;