7-羟基-4-甲氧基-6-氮杂吲哚合成路线 （共 4 条）
反应条件
1-methyl-pyrrolidin-2-one in water T=90°C; 4 h;
参考文献
US2007/249579 A1, ;
Page/Page column 119 ;
反应条件
chloro-trimethyl-silane; sodium iodide in acetonitrile T=65°C; 3 h;
参考文献
Gesenberg, Kirsten; Deshpande, Prashant P.; Pullockaran, Annie; Xu, Feng; Wu, Dedong; Gao, Qi; Pathirana, Charles; Castoro, John; Soundararajan, Nachimuthu; Staab, Andrew
Tetrahedron Letters, 2007 , vol. 48, # 15 p. 2675 - 2677
反应条件
trichlorophosphate T=100°C; 18 h;
参考文献
US2007/249579 A1, ;
Page/Page column 119 ;
反应条件
1: With phosphorus oxytribromide in methoxybenzene
T=160°C; 1 h;
2: With hydrogen bromide in water; methoxybenzene
T=20°C;
3: in tert-butyl methyl ether; water; methoxybenzene
pH=6 - 7;
参考文献
Bristol-Myers Squibb Company
Patent: US2007/249624 A1, 2007 ;
Location in patent: Page/Page column 25 ;
