iodine; sodium hydrogencarbonate in chloroform; water T=70°C; 4 h;

1: 94 percent / K2CO3 / acetonitrile / 60 h / Heating 2: 100 percent / NaOH; water / ethanol / 1 h / Heating 3: 81 percent / N-iodosuccinimide; 2,6-lutidine / CH2Cl2 / 3.5 h / -20 °C View Scheme