3-溴-7-甲氧基-1,2-二氢萘合成路线 （共 4 条）
反应条件
anhydrous magnesium carbonate in diethylene glycol dimethyl ether; water
22 h; Heating;
参考文献
Mandal, Asok N.; Bhattacharya, Sudin; Raychaudhuri, Swadesh R.; Chatterjee, Amareshwar
Journal of Chemical Research, Miniprint, 1988 , # 11 p. 2856 - 2876
反应条件
toluene-4-sulfonic acid in toluene
2 h; Heating;
参考文献
Voets, Marieke; Antes, Iris; Scherer, Christiane; Mueller-Vieira, Ursula; Biemel, Klaus; Marchais-Oberwinkler, Sandrine; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2222 - 2231
反应条件
1: 2-bromo-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-one
2: With toluene-4-sulfonic acid in benzene
3 h; Heating;
参考文献
Wu, Yao-Ting; Noltemeyer, Mathias; De Meijere, Armin
European Journal of Organic Chemistry, 2005 , # 13 p. 2802 - 2810
反应条件
1: 95 percent / tetrabutylammonium tribromide / methanol; CH2Cl2 / 20 °C
2: 86 percent / NaBH4 / methanol; tetrahydrofuran / 0.75 h / 0 - 20 °C
3: 60 percent / p-toluenesulfonic acid / toluene / 2 h / Heating
View Scheme
参考文献
Voets, Marieke; Antes, Iris; Scherer, Christiane; Mueller-Vieira, Ursula; Biemel, Klaus; Marchais-Oberwinkler, Sandrine; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2222 - 2231
