4-[2-(4-吡啶)乙炔]苯甲醛合成路线 （共 6 条）
反应条件
manganese(IV) oxide in dichloromethane
1 h;
参考文献
GENELABS TECHNOLOGIES, INC.
Patent: WO2009/11787 A1, 2009 ;
Location in patent: Page/Page column 77 ;
反应条件
diethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide
24 h;
参考文献
Halper, Sara R.; Do, Loi; Stork, Jay R.; Cohen, Seth M.
Journal of the American Chemical Society, 2006 , vol. 128, # 47 p. 15255 - 15268
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride
Sonogashira coupling; 2 h; Heating;
参考文献
Richardson, Christopher; Reed, Christopher A.
Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4750 - 4755
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride
Sonogashira coupling; 2 h; Heating;
参考文献
Richardson, Christopher; Reed, Christopher A.
Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4750 - 4755
反应条件
1: CuI; Et3N; PPh3 / PdCl2(PPh3)2 / tetrahydrofuran / 8 h / 20 °C
2: 0.78 g / K2CO3; MeOH / 1.5 h / 20 °C
3: 80 percent / CuI; Et3N / PdCl2(PPh3)2 / 2 h / Heating
View Scheme
参考文献
Richardson, Christopher; Reed, Christopher A.
Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4750 - 4755
反应条件
1: 0.78 g / K2CO3; MeOH / 1.5 h / 20 °C
2: 80 percent / CuI; Et3N / PdCl2(PPh3)2 / 2 h / Heating
View Scheme
参考文献
Richardson, Christopher; Reed, Christopher A.
Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4750 - 4755
