3-(4-氯苄基)-6-溴-2-氯喹啉合成路线 （共 5 条）
反应条件
trichlorophosphate in N,N-dimethyl-formamide
T=5 - 80°C; 12 h;
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: WO2008/68268 A1, 2008 ;
Location in patent: Page/Page column 46 ;
反应条件
trichlorophosphate
T=5 - 80°C; 12 h;
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: WO2008/68266 A1, 2008 ;
Location in patent: Page/Page column 53 ;
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: WO2007/436 A1, 2007 ;
Location in patent: Page/Page column 36 ;
反应条件
in methanol
15 h; Heating / reflux;
参考文献
Guillemont, Jerome Emile Georges; Dorange, Ismet; Lancois, David Francis Alain; Villalgordo-Soto, Jose Manuel; Ferdinand, Yvan Rene; Motte, Magali Madeleine Simone; Andries, Koenraad Jozef Lodewijk Marcel; Koul, Anil
Patent: US2010/63026 A1, 2010 ;
Location in patent: Page/Page column 31-32 ;
反应条件
15 h; Heating / reflux;
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: WO2008/68272 A2, 2008 ;
Location in patent: Page/Page column 74 ;
