N-(3,5-二氟苯基)丙烷-1-磺酰胺合成路线 (共 2 条)
反应条件
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / -78 - 0 °C / Inert atmosphere 1.2: 1.5 h / -78 - 110 °C / Microwave irradiation 2.1: potassium carbonate / methanol; water / 0.5 h / 130 °C / Microwave irradiation View Scheme
参考文献
Buck, Jason R.; Saleh, Sam; Imam Uddin, Md.; Manning, H. Charles
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4161 - 4165
反应条件
pyridine in dichloromethane
参考文献
PLEXXIKON, INC.
Patent: WO2008/79909 A1, 2008 ;
Location in patent: Page/Page column 70 ;