acetic acid in tetrahydrofuran; hexane T=20°C; 1 h;

1: lithium 2,2,6,6-tetramethylpiperidine / tetrahydrofuran; hexane / -78 - 20 °C 2: 3.68 g / glacial AcOH / tetrahydrofuran; hexane / 1 h / 20 °C View Scheme

potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; toluene T=100°C; 6 h;