1: With ammonium acetate; sodium cyanoborohydride in methanol
T=20°C; 48 h;
2: With hydrogenchloride in methanol; water
pH=2;
3: With sodium hydroxide in water
pH=10;
参考文献
Bristol-Myers Squibb Company
Patent: US2007/3539 A1, 2007 ;
Location in patent: Page/Page column 63 ;
US 20070003539 A1