N-(苄基磺酰基)-哌啶-4-羧酰胺合成路线 （共 2 条）
参考文献
ASTRAZENECA AB
Patent: WO2008/4945 A1, 2008 ;
Location in patent: Page/Page column 25 ;
反应条件
1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; lithium chloride; triethylamine / acetonitrile / 17 h / 15 - 25 °C / |Inert atmosphere; |Large scale
2: formic acid / 16 h / |Inert atmosphere
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参考文献
Andersen, Soren M.; Aurell, Carl-Johan; Zetterberg, Fredrik; Bollmark, Martin; Ehrl, Robert; Schuisky, Peter; Witt, Anette
Organic Process Research and Development, 2013 , vol. 17, # 12 p. 1543 - 1551
