6-氯-5-氰基-2-甲基烟酰氯合成路线 （共 4 条）
反应条件
N-ethyl-N,N-diisopropylamine T=20°C; 1 h;
参考文献
ASTRAZENECA AB
Patent: WO2007/8140 A1, 2007 ;
Location in patent: Page/Page column 173 ;
WO 2007/008140 A1
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane
T=0 - 20°C; 16.8333 h; Product distribution / selectivity;
参考文献
ASTRAZENECA AB
Patent: WO2007/8140 A1, 2007 ;
Location in patent: Page/Page column 173 ;
WO 2007/008140 A1
反应条件
oxalyl dichloride in dichloromethane
T=80°C; 1 h; Product distribution / selectivity;
参考文献
ASTRAZENECA AB
Patent: WO2007/8140 A1, 2007 ;
Location in patent: Page/Page column 141 ;
WO 2007/008140 A1
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C; 16 h;
参考文献
ASTRAZENECA AB
Patent: WO2007/8140 A1, 2007 ;
Location in patent: Page/Page column 142 ;
WO 2007/008140 A1
