potassium hydroxide in methanol; water T=60°C;

lithium aluminium tetrahydride in tetrahydrofuran T=0°C;

<b>Multi-step reaction with 3 steps<br /> </b>1: 95 percent / LiAlH₄ / tetrahydrofuran / 2 h / 20 &deg;C<br />2: 95 percent / CBr₄; triphenylphosphine / tetrahydrofuran<br />3: 98 percent / potassium carbonate; 18-crown-6 / acetone / 18 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 91 percent / potassium carbonate; 18-crown-6 / acetone / 20 h / Heating<br />2: 95 percent / LiAlH₄ / tetrahydrofuran / 2 h / 20 &deg;C<br />3: 95 percent / CBr₄; triphenylphosphine / tetrahydrofuran<br />4: 98 percent / potassium carbonate; 18-crown-6 / acetone / 18 h / Heating<br /> <br /> &nbsp;