1: n-butyl methanesulphonate With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: With diethyl chlorophosphate in tetrahydrofuran; hexane T=-78 - 50°C; 1.5 h; 3: 5-Bromothiophene-2-carboxaldehyde With n-butyllithium; water more than 3 stages;