2-(4-氨基苯基)-6-甲基苯并噻唑合成路线 （共 28 条）
反应条件
1: bromine; acetic acid
2: aqueous KOH
3: chlorobenzene / Reduzieren des Reaktionsprodukts mit SnCl2 und konz. wss. HCl
View Scheme
参考文献
Schubert
Justus Liebigs Annalen der Chemie, 1947 , vol. 558, p. 10,30
反应条件
triethylamine in dichloromethane
T=20°C; 25 h; Cooling with ice;
参考文献
Biedermann, Frank; Appel, Eric A.; Del Barrio, Jesus; Gruendling, Till; Barner-Kowollik, Christopher; Scherman, Oren A.
Macromolecules, 2011 , vol. 44, # 12 p. 4828 - 4835
参考文献
Weisswange,W.
Diss. <Halle 1925> 49
Full Text Show Details
Siefken
Justus Liebigs Annalen der Chemie, 1949 , vol. 562, p. 75,1114
反应条件
triethylamine in dichloromethane
T=0 - 20°C; Inert atmosphere;
参考文献
Tzanopoulou, Stamatia; Sagnou, Marina; Paravatou-Petsotas, Maria; Gourni, Eleni; Loudos, George; Xanthopoulos, Stavros; Lafkas, Daniel; Kiaris, Hippokratis; Varvarigou, Alexandra; Pirmettis, Ioannis C.; Papadopoulos, Minas; Pelecanou, Maria
Journal of Medicinal Chemistry, 2010 , vol. 53, # 12 p. 4633 - 4641
反应条件
bromine in N,N-dimethyl-formamide
23 h;
参考文献
Karlsson, H. Jonas; Lincoln, Per; Westman, Gunnar
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 6 p. 1035 - 1040
反应条件
bromine; acetic acid
参考文献
Schubert
Justus Liebigs Annalen der Chemie, 1947 , vol. 558, p. 10,30
参考文献
McCapra,F.; Burford,A.
Journal of the Chemical Society, Chemical Communications, 1976 , p. 607 - 608
参考文献
McCapra,F.; Burford,A.
Journal of the Chemical Society, Chemical Communications, 1976 , p. 607 - 608
