dicyclohexyl-carbodiimide in tetrahydrofuran T=0 - 20°C;

1.1: BH3*M2S / tetrahydrofuran / 2 h / 20 °C 1.2: 78 percent / aq. H2O2; NaOH / tetrahydrofuran / 2 h / 20 °C 2.1: 78 percent / aq. NaOH / methanol / 3 h / Heating 3.1: 86 percent / DCC / tetrahydrofuran / 0 - 20 °C View Scheme

1: 78 percent / aq. NaOH / methanol / 3 h / Heating 2: 86 percent / DCC / tetrahydrofuran / 0 - 20 °C View Scheme