methanol; sodium tetrahydroborate T=55 - 60°C; 0.833333 h;

1: potassium carbonate / isopropyl alcohol / 1 h / 50 - 55 °C 2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / dimethyl sulfoxide / 0.5 h / 20 °C 3: methanol; sodium tetrahydroborate / 0.83 h / 55 - 60 °C View Scheme

1: sulfuric acid; water 2: thionyl chloride 3: potassium carbonate / isopropyl alcohol / 1 h / 50 - 55 °C 4: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / dimethyl sulfoxide / 0.5 h / 20 °C 5: methanol; sodium tetrahydroborate / 0.83 h / 55 - 60 °C View Scheme

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / dimethyl sulfoxide / 0.5 h / 20 °C 2: methanol; sodium tetrahydroborate / 0.83 h / 55 - 60 °C View Scheme