2-(2,5-二甲基吡咯-1-基)苯甲酸合成路线 （共 6 条）
反应条件
water; lithium hydroxide hydrate in tetrahydrofuran; methanol T=20°C;
参考文献
DANA-FARBER CANCER INSTITUTE, INC.; WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH; BRADNER, James, E.; MCKEOWN, Michael, R.; RAHL, Peter, B.; YOUNG, Richard, A.; MARINEAU, Jason, J.
Patent: WO2014/71247 A1, 2014 ;
Location in patent: Paragraph 00315 ;
反应条件
acetic acid T=150°C; 4 h; Cooling with ice;
参考文献
Zhu, Weixing; Groh, Matthias; Haupenthal, Joerg; Hartmann, Rolf W.
Chemistry - A European Journal, 2013 , vol. 19, # 26 p. 8397 - 8400
反应条件
1: benzene; acetic acid 2: ethanolic KOH-solution View Scheme
参考文献
Journal of Organic Chemistry, , vol. 20, p. 1443,1445
反应条件
1: benzene; acetic acid 2: ethanolic KOH-solution View Scheme
参考文献
Journal of Organic Chemistry, , vol. 20, p. 1443,1445
反应条件
diazomethane; diethyl ether
参考文献
Journal of Organic Chemistry, , vol. 20, p. 225,228
反应条件
1: diazomethane; diethyl ether View Scheme
参考文献
Shirley et al.
Journal of Organic Chemistry, 1955 , vol. 20, p. 225,228
