in tetrahydrofuran T=0°C; 2.5 h;

1: With chloro-trimethyl-silane; copper(I) thiophene-2-carboxylate; (R)-p-tol-BINAP in diethyl ether; toluene T=-78°C; Inert atmosphere; 2: With hydrogenchloride in methanol; diethyl ether; water; toluene Inert atmosphere; optical yield given as percent eeenantioselective reaction;

1: With chloro-trimethyl-silane; copper(I) thiophene-2-carboxylate; (R)-p-tol-BINAP in diethyl ether T=-78°C; Inert atmosphere; 2: With hydrogenchloride in methanol; diethyl ether; water Inert atmosphere; optical yield given as percent eeenantiospecific reaction;

copper(I) thiophene-2-carboxylate; C19H31N2O(1+)*F6P(1-) in diethyl ether T=-78°C; 8 h; Inert atmosphere;

copper(I) thiophene-2-carboxylate; (S)-MeO-BIPHEP in diethyl ether T=-78°C; 8 h; Inert atmosphere; optical yield given as percent ee;

1: With copper(I) thiophene-2-carboxylate; (R)-p-tol-BINAP in diethyl ether T=-78°C; 8 h; Inert atmosphere; 2: Inert atmosphere; optical yield given as percent ee;

1: With copper(I) thiophene-2-carboxylate; (R)-1,1'-bis(diphenylphosphino)-2,2'-binapthyl in hexane; dichloromethane T=0°C; Inert atmosphere; 2: With hydrogenchloride in hexane; dichloromethane; water Inert atmosphere; optical yield given as percent eeenantioselective reaction;

copper(II) bis(trifluoromethanesulfonate) in diethyl ether T=-78°C; 8 h; optical yield given as percent ee;