1: sulfuric acid / Reflux 2: iron; ammonium chloride / tetrahydrofuran; ethanol; water / 1 h / 85 °C 3: triethylamine / dichloromethane / 0 - 20 °C 4: potassium tert-butylate / dimethyl sulfoxide / 1 h / 15 °C 5: trichlorophosphate / acetonitrile / Inert atmosphere; Reflux 6: hydrogenchloride / water / 6 h / Reflux View Scheme

1: potassium tert-butylate / dimethyl sulfoxide / 4 h / 100 °C 2: iron; hydrogenchloride / ethanol; water / 1.5 h / 80 °C 3: acetic acid / N,N-dimethyl-formamide / 12 h / 60 °C View Scheme

1: trichlorophosphate / acetonitrile / Inert atmosphere; Reflux 2: hydrogenchloride / water / 6 h / Reflux View Scheme

1: triethylamine / dichloromethane / 0 - 20 °C 2: potassium tert-butylate / dimethyl sulfoxide / 1 h / 15 °C 3: trichlorophosphate / acetonitrile / Inert atmosphere; Reflux 4: hydrogenchloride / water / 6 h / Reflux View Scheme

1: iron; ammonium chloride / tetrahydrofuran; ethanol; water / 1 h / 85 °C 2: triethylamine / dichloromethane / 0 - 20 °C 3: potassium tert-butylate / dimethyl sulfoxide / 1 h / 15 °C 4: trichlorophosphate / acetonitrile / Inert atmosphere; Reflux 5: hydrogenchloride / water / 6 h / Reflux View Scheme

1: potassium tert-butylate / dimethyl sulfoxide / 1 h / 15 °C 2: trichlorophosphate / acetonitrile / Inert atmosphere; Reflux 3: hydrogenchloride / water / 6 h / Reflux View Scheme

1.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 4 h / 150 °C / Sealed tube 2.1: sodium hydroxide / methanol / 0.5 h / 20 °C 3.1: palladium 10 on activated carbon; hydrogen / methanol / 2.17 h / 760.05 Torr 4.1: magnesium sulfate; trifluoroacetic acid / dichloromethane / 3 h / 60 °C / Sealed tube 4.2: pH 9 View Scheme

1.1: sodium hydroxide / methanol / 0.5 h / 20 °C 2.1: palladium 10 on activated carbon; hydrogen / methanol / 2.17 h / 760.05 Torr 3.1: magnesium sulfate; trifluoroacetic acid / dichloromethane / 3 h / 60 °C / Sealed tube 3.2: pH 9 View Scheme

1.1: water; palladium diacetate / 20 °C / Inert atmosphere 2.1: 2,6-dimethylpyridine; trifluoroacetic anhydride / toluene / -50 °C / Inert atmosphere; Reflux 3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 4 h / 150 °C / Sealed tube 4.1: sodium hydroxide / methanol / 0.5 h / 20 °C 5.1: palladium 10 on activated carbon; hydrogen / methanol / 2.17 h / 760.05 Torr 6.1: magnesium sulfate; trifluoroacetic acid / dichloromethane / 3 h / 60 °C / Sealed tube 6.2: pH 9 View Scheme

1: sodium methylate / methanol 2: triethylamine / dichloromethane / 2.17 h 3: hydrogenchloride / trans-1,3-dioxane / 24 h / 20 °C 4: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C View Scheme