1-羟基-4-(甲基硫代)-2-丁基氨基甲酸叔丁酯合成路线

参考文献

MERCK SHARP and DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank
Patent: WO2013/52394 A1, 2013 ;
Location in patent: Paragraph 00313 ;

502-83-0DL-蛋氨醇+

24608-52-4叔-丁基氯甲酸酯

92148-47-51-羟基-4-(甲基硫代)-2-丁基氨基甲酸叔丁酯

参考文献

Sandrin,E.; Boissonas,R.A.
Helvetica Chimica Acta, 1966 , vol. 49, p. 76 - 82

63-68-3蛋氨酸

92148-47-51-羟基-4-(甲基硫代)-2-丁基氨基甲酸叔丁酯

参考文献

MERCK SHARP and DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank
Patent: WO2013/52394 A1, 2013 ;

10332-17-9(2S)-2-氨基-4-甲硫基丁酸甲酯

92148-47-51-羟基-4-(甲基硫代)-2-丁基氨基甲酸叔丁酯

参考文献

MERCK SHARP and DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank
Patent: WO2013/52394 A1, 2013 ;