4,7-二甲氧基-1,10-菲咯啉合成路线 （共 7 条）
反应条件
1: 4,7-diol-1,10-phen With sodium hydride in tetrahydrofuran; N,N-dimethyl-formamide; mineral oil T=0°C; 0.5 h; Inert atmosphere; 2: methyl iodide in tetrahydrofuran; N,N-dimethyl-formamide; mineral oil T=20°C; Inert atmosphere;
参考文献
Liu, Xiang; Li, Xiaoyong; Chen, Yu; Hu, Yimin; Kishi, Yoshito
Journal of the American Chemical Society, 2012 , vol. 134, # 14 p. 6136 - 6139
反应条件
1: 86 percent / diphenyl ether / 0.5 h / Heating 2: POCl3 / 2 h / Heating 3: 16.7 g / methanol / 24 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 16 p. 6190 - 6199
反应条件
sodium methylate 1 h; Heating;
参考文献
Levis, Michael; Luening, Ulrich; Mueller, Michael; Schmittel, Michael; Woehrle, Clemens
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1994 , vol. 49, # 5 p. 675 - 682
反应条件
1: POCl3 / 2 h / Heating 2: 16.7 g / methanol / 24 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 16 p. 6190 - 6199
反应条件
1.1: 2 h / 100 °C 1.2: 77 percent / 1 h / 100 °C 2.1: 86 percent / diphenyl ether / 0.5 h / 260 °C 3.1: POCl3 / 2 h / Heating 4.1: 16.7 g / Na / 24 h / 65 °C View Scheme
参考文献
Organic Letters, , vol. 8, # 13 p. 2779 - 2782
反应条件
methanol; copper T=160°C;
参考文献
Journal of Organic Chemistry, , vol. 27, p. 3878,3880
反应条件
copper(l) iodide; caesium carbonate in toluene T=80°C; 12 h;
参考文献
Journal of Organic Chemistry, , vol. 73, # 1 p. 284 - 286
