4-(2-(三氟甲基)苯氧基)哌啶-1-羧酸叔丁酯合成路线 （共 4 条）
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=0 - 70°C; 25 h;
参考文献
PIERRE FABRE MEDICAMENT; Leroy, Isabelle; Dupont-Passelaigue, Elisabeth; Mialhe, Samuel; Junquero, Didier; Valeille, Karine
Patent: US2013/40928 A1, 2013 ;
Location in patent: Paragraph 0212; 0213 ;
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=0 - 20°C;
参考文献
WO2006/130986 A1, ;
Page/Page column 36-37 ;
WO 2006/130986 A1
反应条件
diethylazodicarboxylate in tetrahydrofuran T=0 - 20°C; 14 h;
参考文献
WO2008/17161 A1, ;
Page/Page column 28-29 ;
WO 2008/017161 A1
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 24 h;
参考文献
PIERRE FABRE MEDICAMENT; Leroy, Isabelle; Dupont-Passelaigue, Elisabeth; Mialhe, Samuel; Junquero, Didier; Valeille, Karine
Patent: US2013/40928 A1, 2013 ;
Location in patent: Paragraph 0212; 0213 ;
