[1,1′:4′,1″]三联苯-3,3″,5,5″-四甲酸合成路线 （共 5 条）
反应条件
1: K3PO4 / Pd(PPh3)4 / dioxane / 72 h / 80 °C
2: 0.28 g / aq. NaOH / Heating
View Scheme
参考文献
Lin, Xiang; Jia, Junhua; Zhao, Xuebo; Thomas, K. Mark; Blake, Alexander J.; Walker, Gavin S.; Champness, Neil R.; Hubberstey, Peter; Schroeder, Martin
Angewandte Chemie - International Edition, 2006 , vol. 45, # 44 p. 7358 - 7364
反应条件
sodium hydroxide in tetrahydrofuran; methanol
T=60°C;
参考文献
Park, Jinhee; Wang, Zhiyong U.; Sun, Lin-Bing; Chen, Ying-Pin; Zhou, Hong-Cai
Journal of the American Chemical Society, 2012 , vol. 134, # 49 p. 20110 - 20116
反应条件
1: palladium diacetate; potassium acetate / N,N-dimethyl-formamide / 12 h / 90 °C / |Schlenk technique; |Inert atmosphere
2: cesium fluoride; tetrakis(triphenylphosphine) palladium(0) / ethylene glycol dimethyl ether / 48 h / |Reflux; |Inert atmosphere
3: sodium hydroxide / tetrahydrofuran; methanol / 60 °C
View Scheme
参考文献
Park, Jinhee; Wang, Zhiyong U.; Sun, Lin-Bing; Chen, Ying-Pin; Zhou, Hong-Cai
Journal of the American Chemical Society, 2012 , vol. 134, # 49 p. 20110 - 20116
反应条件
1: cesium fluoride; tetrakis(triphenylphosphine) palladium(0) / ethylene glycol dimethyl ether / 48 h / |Reflux; |Inert atmosphere
2: sodium hydroxide / tetrahydrofuran; methanol / 60 °C
View Scheme
参考文献
Park, Jinhee; Wang, Zhiyong U.; Sun, Lin-Bing; Chen, Ying-Pin; Zhou, Hong-Cai
Journal of the American Chemical Society, 2012 , vol. 134, # 49 p. 20110 - 20116
反应条件
1.1: hydrogenchloride; sodium nitrite / water / 1 h / 0 - 5 °C
1.2: 12 h / 0 - 20 °C
2.1: palladium diacetate; potassium acetate / N,N-dimethyl-formamide / 12 h / 90 °C / |Schlenk technique; |Inert atmosphere
3.1: cesium fluoride; tetrakis(triphenylphosphine) palladium(0) / ethylene glycol dimethyl ether / 48 h / |Reflux; |Inert atmosphere
4.1: sodium hydroxide / tetrahydrofuran; methanol / 60 °C
View Scheme
参考文献
Park, Jinhee; Wang, Zhiyong U.; Sun, Lin-Bing; Chen, Ying-Pin; Zhou, Hong-Cai
Journal of the American Chemical Society, 2012 , vol. 134, # 49 p. 20110 - 20116
