2-氨基-3,7,8-三甲基-3H-咪唑并[4,5-f]喹噁啉合成路线 （共 12 条）
反应条件
1: 78 percent / Ac2O / 1.25 h / Ambient temperature 2: 74 percent / LiAlH4 / tetrahydrofuran / 4 h / 0 - 5 °C 3: 54 percent / conc. H2SO4, KNO3 / acetic acid / 2 h / 20 °C 4: 1.) H2 / 1.) Raney nickel / 1.) EtOH, 40-45 min, 2.) 20 deg C, 3.5 h View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
反应条件
1: 1.) H2 / 1.) Raney nickel / 1.) EtOH 2: 17 percent / H2O / 200 °C View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
反应条件
1: 84 percent / Bu4N+OH-, NaOH / CH2Cl2 / 0.83 h / Heating 2: 37 percent / conc. H2SO4, KNO3 / acetic acid / 2 h / 20 °C 3: 1.) H2 / 1.) Raney nickel / 1.) EtOH, 40-45 min, 2.) 20 deg C, 3.5 h View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
反应条件
1: 37 percent / conc. H2SO4, KNO3 / acetic acid / 2 h / 20 °C 2: 1.) H2 / 1.) Raney nickel / 1.) EtOH, 40-45 min, 2.) 20 deg C, 3.5 h View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
反应条件
1: 63 percent / 26 h / 200 °C 2: 54 percent / conc. H2SO4, KNO3 / acetic acid / 2 h / 20 °C 3: 1.) H2 / 1.) Raney nickel / 1.) EtOH, 40-45 min, 2.) 20 deg C, 3.5 h View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
反应条件
1: 74 percent / LiAlH4 / tetrahydrofuran / 4 h / 0 - 5 °C 2: 54 percent / conc. H2SO4, KNO3 / acetic acid / 2 h / 20 °C 3: 1.) H2 / 1.) Raney nickel / 1.) EtOH, 40-45 min, 2.) 20 deg C, 3.5 h View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
反应条件
1: LiAlH4 / tetrahydrofuran / 0 - 5 °C 2: 54 percent / conc. H2SO4, KNO3 / acetic acid / 2 h / 20 °C 3: 1.) H2 / 1.) Raney nickel / 1.) EtOH, 40-45 min, 2.) 20 deg C, 3.5 h View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
反应条件
1: 54 percent / conc. H2SO4, KNO3 / acetic acid / 2 h / 20 °C 2: 1.) H2 / 1.) Raney nickel / 1.) EtOH, 40-45 min, 2.) 20 deg C, 3.5 h View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
反应条件
hydrogen; nickel 1.) EtOH, 40-45 min, 2.) 20 deg C, 3.5 h; Yield given. Multistep reaction;
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 6 p. 486 - 492
