1: 91 percent / aq. KOH / CH2Cl2 / overnight 2: 60 percent / 90percent HNO3 / 0.5 h / -2 - 2 °C 3: 95 percent / aq. NaOH / methanol / 0.5 h / Heating 4: 83 percent / K2CO3 / acetone / 84 h / Heating 5: 96 percent / hydroxylamine hydrochloride, HCOOH / 2 h / Heating 6: 88 percent / Fe powder, glacial acetic acid / propan-2-ol / 0.08 h / Heating 7: 73 percent / NaHCO3 / CHCl3 / 2 h / Heating 8: 11 percent / diethyl ether; dioxane / 4 h / Heating View Scheme

1: 83 percent / K2CO3 / acetone / 84 h / Heating 2: 96 percent / hydroxylamine hydrochloride, HCOOH / 2 h / Heating 3: 88 percent / Fe powder, glacial acetic acid / propan-2-ol / 0.08 h / Heating 4: 73 percent / NaHCO3 / CHCl3 / 2 h / Heating 5: 11 percent / diethyl ether; dioxane / 4 h / Heating View Scheme

potassium permanganate in acetone 96 h; Ambient temperature;

1: aq. NaOH / tetrahydrofuran / 2 h / Ambient temperature 2: 74 percent / NH4OAc / 2 h / Heating View Scheme

1: 96 percent / sodium acetate, H2 / PtO2 / ethyl acetate / 24 h / 2585.7 Torr 2: 57 percent / 2.) aq. NaOH / tetrahydrofuran / Ambient temperature; 1.) exothermic reaction, 2.)room temperature, 2 h; 3: 85 percent / aq. HCl / acetone / 4 h / Ambient temperature 4: 54 percent / NH3 / ethanol / 6 h / 130 °C 5: 88 percent / tetrahydrofuran; diethyl ether / 1.) room temperature, 16 h, 2.) reflux, 2 h; 6: 11 percent / KMnO4 / acetone / 96 h / Ambient temperature View Scheme

1: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C, 30 min 2: 88 percent / Ac2O / heptane / 1 h / Heating 3: 94 percent / tetrahydrofuran; diethyl ether / 0.5 h / 0 °C 4: 61 percent / 25percent H2SO4 / butan-1-ol / 7.5 h / Heating 5: 91 percent / AcOH / H2O / 2 h / Ambient temperature View Scheme

1: 90 percent / 2 N NaOH / CH2Cl2 / 1 h / Ambient temperature 2: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 2.) THF, hexane, 0 deg C, 30 min 3: 88 percent / Ac2O / heptane / 1 h / Heating 4: 94 percent / tetrahydrofuran; diethyl ether / 0.5 h / 0 °C 5: 61 percent / 25percent H2SO4 / butan-1-ol / 7.5 h / Heating 6: 91 percent / AcOH / H2O / 2 h / Ambient temperature View Scheme

1: 61 percent / 25percent H2SO4 / butan-1-ol / 7.5 h / Heating 2: 91 percent / AcOH / H2O / 2 h / Ambient temperature View Scheme

1: 77 percent / sodium dichromate, conc. H2SO4 / H2O / 2 h / Heating 2: 61 percent / 25percent H2SO4 / butan-1-ol / 7.5 h / Heating 3: 91 percent / AcOH / H2O / 2 h / Ambient temperature View Scheme

1: 94 percent / tetrahydrofuran; diethyl ether / 0.5 h / 0 °C 2: 61 percent / 25percent H2SO4 / butan-1-ol / 7.5 h / Heating 3: 91 percent / AcOH / H2O / 2 h / Ambient temperature View Scheme