n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C;

1: n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C 2: n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C View Scheme

1: 87 percent / PdCl2(PPh3)2; CuI; Et3N / 18 h / 20 °C 2: n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C 3: n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C View Scheme