1: 2-[(diphenylmethylene)amino]acetamide With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane; water 0.05 h; 2: methyl iodide in dichloromethane; water T=20°C;

in N,N-dimethyl-formamide T=20°C;

1.1: 70 percent / triethylamine / 1,2-dichloro-ethane / Heating 2.1: NaOH; tetrabutylammonium hydrogen sulfate / H2O; CH2Cl2 / 0.05 h 2.2: 84 percent / H2O; CH2Cl2 / 20 °C View Scheme