反应条件
1: ethyl acetate
2: thionyl chloride / dichloromethane / 20 °C / |Inert atmosphere
3: potassium carbonate / N,N-dimethyl-formamide / 80 °C / |Inert atmosphere
4: sodium hydroxide / water / |Reflux; |Inert atmosphere
View Scheme
参考文献
Smethurst, Chris A.; Bevan, Nicola; Emmons, Amanda; Mookherjee, Claudette; Moores, Kitty; Peace, Simon; Piercy, Val; Watson, Steve P.; Zippoli, Mara; Brooks, Carl; Gough, Peter J.; Philp, Joanne
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 23 p. 7252 - 7255,4
Title/Abstract Full Text Show Details
Smethurst, Chris A.; Bevan, Nicola; Brooks, Carl; Emmons, Amanda; Gough, Peter J.; Mookherjee, Claudette; Moores, Kitty; Peace, Simon; Philp, Joanne; Piercy, Val; Watson, Steve P.; Zippoli, Mara
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 23 p. 7252 - 7255
